ABSTRACT
Calcifying cystic odontogenic tumor (CCOT) are uncommon benign slow-growing cysts of developmental origin partly exhibiting characteristics of a neoplasm. Until date, the exact behavior of CCOT had been enigmatic and still the lesion portrays a platform to be debatable. The lesion has been reviewed and readdressed from the date first reported about its diverse clinical and histopathological features. The name of the lesion itself has undergone extensive review for the same reason. We report a case of calcifying odontogenic cyst in the mandible with a review of the literature. This paper also highlights the update on nomenclature and classification.
Subject(s)
Asymptomatic Diseases , Female , Humans , Mandible/pathology , Middle Aged , Odontogenic Cyst, Calcifying/classification , Odontogenic Cyst, Calcifying/diagnosis , Odontogenic Cyst, Calcifying/pathology , Odontogenic Cyst, Calcifying/diagnostic imaging , Odontogenic Cyst, Calcifying/surgery , Review Literature as TopicABSTRACT
Introdução: os cistos odontogênicos constituem uma importante doença oral e maxilo-facial. Embora alguns possam resultar da inclusão de epitélio na linha de fusão de processos embrionários, muitos são limitados por epit[elio de origem odontogênica. Podem ser classificados em cistos de desenvolvimento e inflamatórios, de acordo com sua origem. Pacientes e método: os autores realizaram um estudo retrospectivo da incidência de cistos odontogênicos em pacientes atendidos no ambulatório do Serviço de Cabeça e Pescoço do Centro de Oncologia (CEON) do Hospital Universitário Oswaldo Cruz (HUCC)e registrados no Centro Integrado de Anatomia Patológica (CIAP), no período de janeiro de 1980 a janeiro de 2000. No presente estudo, 72 pacientes portadores de cistos odontogênicos foram arrolados. Foram analisados os indicadores tipo histopatológico, gênero, localização topográfica e faixa etária. Resultados: usando a classificação preconizada pela Organização Mundial da Saúde, 54,1% foram cistos dentígeros; 4,1% cisto odontogênico calcificante; 2,8% ceratocistos odontogênicos e 36,2% foram cistos de origem odontogênica, todavia, não identificados quanto ao tipo histopatológico. A maior parte das lesões císticas foi encontrada na maxila (61,1%). Conclusão: o conhecimento de sua origem e achados clinico-patológicos dessas lesões sáo aspectos básicos para realizar um diagnóstico precoce e um tratamento apropriado.
Introduction: the odontogenic cysts are an important oral and maxillofacial disease. Some cysts can be the result of epithelial inclusion into the fusion line of embryonic process. Howrever, others are limited by epithelium of odontogenic origin. They can be classified in developmental and inflammatory cysts according to their origin. Patients and methods: the authors performed the retrospective study of the incidence of odontogenic cysts in patients from the Service of Head and Neck Surgery, Centro de Oncologia (CEON), Hospital Universitário Oswaldo Cruz (HUOC) and registered in Centro Integrado de Anatomia Patológica (CIAP) from January, 1980 to January, 2000. A total of 72 patients with odontogenic cysts were enrolled in this study. The histopathologic type, gender, topographic place and age were analyzed. Results: according to the WHO classification, our findings were as following: dental cysts, 54.1%; calcified odontogenic cysts, 4.1%; apical periodontal cysts, 2.8%; odontogenic ceratocysts, 2.8%; and odontogenic cysts without histophatologic identification, 36.2%. Most part of the cystic lesions were found in the maxilla (61.1%). Conclusion: the knowledge of the origin and the clinic-pathological findings are important aspects in order to perform early diagnosis and adequate treatment.
Subject(s)
Humans , Male , Female , Infant , Child, Preschool , Child , Adolescent , Adult , Middle Aged , Aged, 80 and over , Odontogenic Cyst, Calcifying/epidemiology , Brazil/epidemiology , Odontogenic Cyst, Calcifying/classification , Age Distribution , Sex Distribution , Retrospective Studies , IncidenceABSTRACT
Calcifying odontogenic cyst(COC) is an uncommon developmental odontogenic cyst and was first described by Gorlin in 1962. It is considered as extremely rare and accounts for only 1% of the jaw cysts reported. Here, we present two cases of which one occurred in a 32 year old female with a swelling in the lower anterior region crossing the midline and another in a 29 year old male with a swelling in the upper anterior region without crossing the midline. The radiograph revealed a well circumscribed radiolucency in the first case and with some specks of opacities in the second case. It was not associated with any missing or impacted tooth. Histopathological examination was done with Hematoxylin and Eosin and in addition it was studied immunohistochemically for cytokeratin. The Classical histological features of lining epithelium in the form of cords, presence of ghost cells and some amount of dentinoid tissue were seen. The nature of COC is controversial. Here we have discussed the controversies regarding COC as well as the various proposed classifications for this lesion. Based on the histopathological findings, the diagnosis was confirmed as calcifying odontogenic cyst. These cases are presented here for its rarity.